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doi: 10.1016/j.drugalcdep.2015.10.015

In a PD mouse model induced by intraperitoneal injection of salsolinol (SAL), and in SAL-treated SH-SY5Y cells, GSH expression was significantly reduced, whereas levels of ROS, Fe 2+ , ACSL4, MDA, 4-HNE, and -Syn were markedly elevated

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The outer thigh, midway between the hip and the knee, is a reliable subcutaneous injection site and is the preferred alternative when the abdomen is uncomfortable or if site rotation requires a break from abdominal injections

This energetic role is usually considered in the context of the specific vulnerability to TD of tissues with high energy demand, such as the heart and the brain