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Numerous compounds have been used to inhibit the activity of endogenous mammalian G6PDH in vitro and/or in vivo such as the naturally occurring adrenal steroid dehydroepiandrosterone (DHEA) 3 , catechin gallates, especially epigallocatechin gallate (EGCG) 4 , chelerythrine (initially a PKC inhibitor) and PP2 (Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine), primarily a Src kinase family inhibitor 5

mTBI includes concussion, subconcussion, and certain blast injuries related to improvised explosive devices [38]

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However, because of its rarity, it is highly unlikely that all 30 subjects had inherited TCI deficiency

The therapy may also complement wellness strategies for maintaining skin health, promoting collagen synthesis, and supporting detoxification of environmental or metabolic byproducts

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