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In pernicious anaemia, the immune system mistakenly attacks the gastric parietal cells that produce intrinsic factor, leading to B12 deficiency over time

Originally, BPC 157 appears as a cytoprotective antiulcer peptide, stable in human gastric juice, previously employed in ulcerative colitis clinical trials and now in those concerning multiple sclerosis (Sikiric et al., 1993

The Importance of Vitamin B12 Vitamin B12 is a water-soluble vitamin essential for several critical processes in the body

The animals were treated daily during five weeks with L-NAME (10 mg/kg b.w.), L-arginine (100 mg/kg b.w.), NaBPC157 (10 g/kg b.w.) and their combinations (L-NAME + NaBPC157, L-NAME + L-arginine) intraperitoneally

We tailor depth by zone, balancing visible change with practical downtime

10.1158/1078-0432.CCR-06-2642 136 MenchiniR