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In Phase-2 studies : 24 % weight loss at max dose- 86 % reduction in liver fat Key outcomes: LS mean % weight change at 48 weeks: 8.7% (1 mg), 17.1% (4 mg), 22.8% (8 mg), 24.2% (12 mg) vs 2.1% placebo

Heavier or obese patients did better with PRP A March 2020 study ( 7 ) compared platelet-rich plasma was better than hyaluronic acid for the treatment of knee osteoarthritis in overweight or obese patients

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Key Findings: Oral cobalamin supplementation can be an effective alternative to parenteral injections
