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Pharmacology-Relevant Design Features The small tripeptide structure of GHK contributes to its ability to rapidly coordinate copper ions and form a stable peptidemetal complex suitable for experimental applications

The in vivo results indicate that Rg3-Exo/ATO@Ce6 notably inhibits orthotopic GBM growth, induces TAMs polarization, and facilitates cytotoxic T lymphocytes infiltration, achieving remarkably improved survival benefits

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It also may cause a reduction in mitochondrial transmembrane potential due to an increase in cytosolic cytochrome complex (Cyt c) levels

Oxylipins were eluted using an ACQUITY UPLC BEH C18 column (1.7 m, 2.1 100 mm