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10.1016/j.bcp.2013.01.017 16 BorrelliF.PaganoE.RomanoB.PanzeraS.MaielloF.CoppolaD.et al (2014)

These inclusion bodies consist mainly of aggregated (clumped-together misfolded protein)

In contrast, forward flux through the TCA cycle was increased upon glucose deprivation in sensitive but not resistant cell lines, as indicated by increased labeling of malate M4 and fumarate M4 upon glucose deprivation (Fig

doi: 10.1152/japplphysiol.01077.2006

Within cellular biology research, FOXO proteins are known to participate in signalling networks that regulate gene expression related to cellular stress responses, metabolic activity and programmed cellular processes
