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Zonulin causes TJ disassembly and thus violates the intestinal barrier ( Polyphenolic compounds (secondary plant metabolites with a long list of beneficial properties for humans) are other food components that improve intestinal integrity

J., Yankaya, B., Leenstra, S
Harms, K

doi: 10.1016/j.tim.2021.01.003 6 LagoumintzisGPatrinosGP

A Comprehensive Review of Fortification, Bioavailability, and Health Benefits of Folate

The expression of HO-1 through NRF-2 depends on the bioavailability of free heme groups, which are toxic for the cells