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Oral forms of some peptides exist, but their effectiveness can be limited due to digestive breakdown

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The most common side effects are nausea, vomiting, constipation, and digestive upset, especially at the beginning of therapy

Moreover, ULK1 directly phosphorylates mitophagy receptors such as FUNDC1, BNIP3, NIX, and BCL2L13 to facilitate mitophagy receptor-mediated mitophagy [207]

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Bigatto, V