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Additionally, TGs protective effect against IPF may involve the MMP system, as TG significantly downregulated MMP-2, MMP-9, and tissue inhibitor of metalloproteinase-1 induced by bleomycin, potentially disrupting basement membrane integrity and mitigating fibroblast invasion (Yang et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Perez H.L., Junnotula V., Knecht D., Nie H., Sanchez Y., Boehm J.C., Booth-Genthe C., Yan H., Davis R., Callahan J.F

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Increased oxidative stress with aging reduces chondrocyte survival: correlation with intracellular glutathione levels

10.2174/1875044301205010055 123 ManautouJ