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This impairment would further exacerbate the disturbance of intracellular Ca 2+ homeostasis, disrupt normal energy metabolism, promote ROS accumulation, and ultimately lead to myocardial excitation-contraction dysfunction (169, 174)

"A healthy cell compensates by reversing the process and when that happens, the redox potential shifts back to its original value

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10.3390/antiox10101608 64 WangZ.JuY.AliZ.YinH.ShengF.LinJ.et al (2019)