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Evidence type: Human RCT | Observational | Animal | In vitro | Regulatory Mechanism of Action 5-Amino-1MQ works by blocking the NNMT enzyme , which is responsible for consuming nicotinamide and depleting NAD+ stores

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It is very important for DNA repair and phosphorylation and is most needed in organs with high energy like the brain and nerves

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People with intestinal disorders like Chrons or Celiac disease, or alcoholics, are also at risk of deficiency

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Optional: Glycerin, propanediol

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By injecting melanoma cells into CD38/ mice, the function of CD38 could be studied and was found to be involved in (1) resistance to cell death, (2) tumor vascularization through a reduction in CD34, (3) recruitment of CAFs and (4) metastatic properties [50]

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