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599 Specifically, PBA treatment reduced the expression of markers of ER stress in the cortex and hippocampus, such as phosphorylated PERK and ATF4, while increasing the expression of the molecular chaperone GRP78

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(3) Multitargeted therapy: BBR-isoliquiritigenin (ISL) dual therapy attenuates adipose inflammation and dyslipidemia via IRS1-PI3K-Akt pathway activation in DIO mouse, while BBR-catechin-capsaicin polypharmacology outperforms monotherapies in 3T3-L1 adipocytes [181, 195]

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En su estado natural es un estereoismero L , una amina cuaternaria sintetizada en el hgado, los riones y el cerebro a partir de dos aminocidos esenciales, la lisina y la metionina

Lin W, Yuan L, Cao Z, Feng Y, Long L
