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Efficacy and safety of rituximab treatment in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis

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Therefore, an effective treatment would be expected to augment synaptic connectivity, protect neurons from underlying death inducers, and stimulate the replacement of lost neurons from pre-existing pools of neural stem cells

Overall, there is still a lack of convincing evidence for the clinical efficacy of functional food actives, and large-scale, high-quality RCTs are urgently needed to facilitate the translation of these actives from the laboratory to clinical applications

This dynamic communication between the mitochondria and the nucleus establishes a finely regulated signaling network, enabling the cell to respond to fluctuating metabolic or stress pressures and adjust gene expression to regulate the cellular senescence process [161]