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As a more severe procedure, chronic unpredictable stress (after 5 d of unpredictable stress protocol, once daily drug application during stress procedure, open field-immobility test assessment at fourth or sixth day of medication) was used

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Repetitive overhead motions can stress the biceps tendon and shoulder, causing irritation in the bicipital groove

Short-term handling at room temperature during active laboratory use is generally acceptable, but frozen storage is recommended between research sessions to preserve peptide integrity