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SAM is sufficient to ensure full repression of ATG genes To establish further the essential contribution of SAM in the transcriptional regulation of ATG genes, we performed depletion-repletion experiments with three combinations of mutations blocking different parts of the sulfur amino acid biosynthesis pathway: SAM synthesis, methionine synthesis, and both cysteine and methionine synthesis (Fig

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doi: 10.1007/s40265-023-01834-3

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Taddei S, Caraccio N, Virdis A, et al