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erinaceus contribute to its anti-inflammatory effects by activating the Nrf2 (nuclear factor erythroid 2-related factor 2) pathway, which enhances the expression of antioxidant enzymes like superoxide dismutase (SOD) and glutathione peroxidase (GPx) (Figure 3C) [120]

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Steady R&D investment in these advanced approaches reflects growing clinical confidence in targeted therapies that address difficult or rare disease pathways