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PLoS One 10:e0130251 Afshar B, Ganjalikhani-Hakemi M, Esfahani ZK, Eskandari N, Shaygannajad V, Hosseininasab F, Alsahebfosoul F (2021) Evaluating the effects of epigallocatechin-3-gallate on HIF-1 protein and rorc gene expression in peripheral blood mononuclear cells in patients with multiple sclerosis

3.4 Connections between genetic mutations and metabolic changes The HPGL/PCC syndrome, where loss-of-function mutations affect SDH and increase intracellular levels of the oncometabolite succinate, thus causing onset of pheochromocytoma and paraganglioma, is a proof-of-concept that metabolic changes can drive tumorigenesis

Here, we reported the influence of SGA monotherapy and combined therapy of SGA with antidepressant, BZD, and mood stabilizer for immune profiles (cytokines, lymphocyte subtypes, and thyroid autoimmune antibodies) on patients with SCZ
