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doi: 10.1016/j.jtemb.2013.08.005 2 BuettnerGRNgCFWangMRodgersVGJSchaferFQ

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There is an extensive body of knowledge regarding the electron transfer mechanisms within enzymatic reactions, including single- and paired-electron transfers

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Natural compounds like midazolam, vitamin B12, metformin, Cangrelor, and hesperidin have also shown anti-inflammatory effects in preclinical MIRI models, often by modulating macrophage polarization or inhibiting inflammatory pathways like NF-B (Xu et al., 2024)