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Although the kinetic (G(r) = 0.1535 a.u.) and potential (V(r) = 0.0512 a.u.) energy densities are relatively substantial, the total energy density remains positive (Hb = 0.204 a.u.) thus yielding a max imum value of VIR (0.2047)

doi: 10.1016/j.ijgo.2007.10.024 32 CriderKSYangTPBerryRJBaileyLB

Unfortunately, the available evidence is of low quality because study cohorts were small, and replication studies are either missing or contradictory (91)

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Wolters PJ, Collard HR, Jones KD (2014) Pathogenesis of idiopathic pulmonary fibrosis

Baicalein was able to down-regulate the activation of poly (ADP-ribose) polymerase (PARP, a DNA repair enzyme and is also a cleavage substrate for caspases) and cas-3 that were increased by gentamicin treatment