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In both cases, analysis of the inclusion bodies produced by polyQ aggregation showed that mutations in unc1 ( e719 and e1598 ) phenocopy the aggregation pattern of vlt10 worms (Fig 1C and D) without altering 40Q::YFP transgene expression (Appendix Fig S1C and D)

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After the first intraspinal partial resection, the diagnosis of MMNST was established

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