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In Japan, gastric emptying was measured in healthy subjects and increased significantly after ingestion of a broth with rice, which was accompanied by a significantly more rapid rise in plasma GLP-1 and glucose levels compared to rice with water (73)

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Moreover, their interaction with membraneassociated receptors, such as prion proteins and spectrin, further exacerbates oxidative stress, elevates ROS levels, reduces ATP production, and disrupts cytoskeletal dynamics [156, 157, 158]

An increasing amount of research associates prediabetes, obesity, and metabolic syndrome with the risk of developing both DPN and chronic sensorimotor peripheral neuropathy (CSPN)