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Major depressive disorder demonstrates Bacteroidetes / Firmicutes ratio elevation contrasting with anxiety disorders, while ASD presents the distinct profile of reduced diversity with increased biomass and concurrent expansion of multiple opportunistic pathogens

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10.5966/sctm.2015-0386 161 WellnerU.SchubertJ.BurkU

In this review, we provide a comprehensive and critical analysis covering the recent advances, potential challenges and future prospects regarding the design and synthesis, as well as pre- and clinical evaluation of cereblon-based PROTACs

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