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[24] [25] According to a study published in 2019, disruption of mitochondrial homeostasis caused by NAD+ depletion is a significant contributor to the metabolic dysfunction in WS
When SOX2 is overexpressed, endogenous SLC7A11 expression is enhanced at both mRNA and protein levels
Neurodegenerative disorders have previously been associated with metabolic abnormalities
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Aagndz D, Ayakda G, Katrcolu B, Ozogul F
10.1038/s41401-019-0273-1 91 QinF.YeY
