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The cardiovascular and respiratory side effects include chest pain, tachycardia (increased heart rate), heart palpitations, low blood pressure, and chest tightness, cough with or without production of pink frothy sputum, wheezing and difficulty breathing

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1991 European Food Safety Authority Panel on Dietetic Products, Nutrition, and Allergies

It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease

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Proper use of modifiers ensures that claims for B12 injections are processed accurately, without unnecessary denials or delays