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Introduction Parkinson's disease (PD) is a multifactorial disease that occurs as a result of factors such as genetic heredity, aging, and environmental factors (Ozansoy and Baak, 2017)

The development of targeted compounds, such as those designed to modulate PINK1 phosphorylation and substrate binding, disrupt the BNIP3/NIX homodimer interface, or act as specific LIR motif competitors, remains highly challenging

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2 Glutamine metabolism Gln is the most abundant amino acid in the human body (11)

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