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But treatment is easy and usually successful if caught in time
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see NHS guidance and Xenical/Alli SmPCs), and injectable GLP-1 receptor agonists such as semaglutide (Wegovy) and liraglutide (Saxenda)

Moreover, in animals, NNMT knockdown improves insulin sensitivity, overnight fasting glucose levels, and glucose tolerance and reduces the relative fat mass [11, 14]

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This pattern is not unique to tirzepatide but reflects the biology of obesity and metabolic adaptation
