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Consequently, mitochondrial dysfunction exacerbates oxidative stress, impairs mitochondrial DNA (mtDNA) or deletions of mtDNA, increases intracellular Ca2+ levels, changes in fission/fusion and mitochondrial morphology, and lastly leads to neuronal death

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Understanding the role of glutathione reductase in cellular health provides crucial insights into addressing its deficiency, affecting red cell glutathione reductase and leading to symptoms such as anemia

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