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Donnelly for critical comments on an early version of this manuscript and P

Eur J Nutr 2015 Mar;54(2):251-263

Nomoto Y, Furihata M, Hagiwara H, Ishino H, Yano S, Okawa H, et al

In our experience, 29.4% (10 of 34) of men in this group have leukocytospermia as opposed to 12.2% (77 of 629) in the general population of men with infertility [unpublished data]

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Metabolic reprogramming driven by oncogenes allows cancer cells to maintain deregulated cell proliferation, withstand metabolic challenges that are associated with diminished oxygen and nutrients, maintain a dedifferentiated state through alterations in global patterns of gene expression, and corrupt the surrounding microenvironment to actively facilitate tumor growth and dissemination 1618