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IGF-I/IGF-binding protein-3 combination improves insulin resistance by GH-dependent and independent mechanisms
[28] found that NNMT knockdown significantly reduced the body weight, fat mass, and insulin level of female mice fed a Western diet (fat 47% kcal, carbohydrate 34% kcal), as did NNMT knockout

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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Mumford S.L., Chavarro J.E., Zhang C., Perkins N.J., Sjaarda L.A., Pollack A.Z., Schliep K.C., Michels K.A., Zarek S.M., Plowden T.C., et al
