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The smallest reported amount of fat causing cerebral embolism is 0.5 mL [25]

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Jul 2012;98(1):126-30

This also proves slightly different mechanisms of lipoprotein circulation in the CNS and the impermeability of both the blood-brain barrier and the blood-cerebrospinal fluid barrier to cholesterol and plasma lipoproteins (except for the precursor of small spherical HDL particles)