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doi: 10.1007/s00266-025-05077-3

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In earlier trials, some patients experienced common adverse effects like injection site pain, rash, headaches, muscle soreness, nausea and fevers

Consequently, the lesions induced in rats share a considerably high degree of similarity with corresponding lesions in human patients

Research reveals that some chemotherapy-induced senescent cells may initially contribute to administration efficacy through SASP-mediated immune activation, but their persistence can promote tumor recurrence and administration resistance
