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Furthermore, the Keap1/NRF2/ARE signaling pathway plays a critical role in tumor cell drug resistance, and PVT1 may further promote the development of resistance by regulating this pathway [169]

10.1371/journal.pone.0095935 PLoS One

Crucially, we address current translational limitations by exploring advanced drug delivery systems, such as nanocarriers and hydrogels, designed to effectively overcome the blood-retinal barrier (BRB) and improve targeted efficacy

doi: 10.3390/toxins12090605

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Therapeutic potential of curcumin in eye diseases