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[DOI] [PubMed] [Google Scholar] 5.Cobalamin related parameters and disease patterns in patients with increased serum cobalamin levels

Because the half-life sits around 6 hours, its a daily compound regardless of route

Where serum B12 results are borderline or do not fit the clinical picture, further tests such as active B12 (holotranscobalamin), methylmalonic acid, or homocysteine may be helpful

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

doi: 10.1038/309163a0

This duration balances therapeutic benefits with manageable treatment commitment and cost considerations
