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Is it Time to Combine Osteoporosis Therapies

2.3 Metabolites analysis 2.3.1 Determination of urinary creatinine Before testing, the samples were naturally thawed at room temperature, then the urine sample was centrifuged at 12000 rpm for 5 min, and the supernatant was ready for use

Unlike single-pathway therapies, Tirzepatide is a dual-action medication that activates both GLP-1 and GIP receptors simultaneously addressing appetite, satiety, insulin response, and fat metabolism

Funding Statement The authors gratefully acknowledge the financial support provided by the Fundao Carlos Chagas de Amparo Pesquisa do Estado do Rio de Janeiro, Brazil, grant numbers [E-26/203.745/2024] and [E-26/200.891/2021], the Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq), grant number [313119/2020-1], and the Coordenao de Aperfeioamento de Pessoal de Nvel Superior (CAPES) Brazil, Finance Code 001

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PubMed Copper supports regulatory T cell energetic state to sustain peripheral