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Drug Research 68: 403409

Evidence from basic science and clinical studies indicate that the intestinal TJ barrier has a critical role in the pathogenesis of intestinal and systemic diseases.1,10 Thus, this review summarizes the molecular structure and regulation of intestinal TJs and the involvement of intestinal TJs in IBD pathogenesis

It can be transmitted or spread in several ways, including (8): Perinatal transmission : One of the most common ways that it spreads in endemic areas is by transmission from mother to child at birth