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History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy

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This makes it hard for them to circulate in your blood and may cause anemia

What is the recommended dose and administration of methylcobalamin solution for vitamin B12 supplementation?

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Many people who try to eat healthier include salmon in their diets