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Effects of folic acid and vitamin B12 supplementation on cognitive impairment and inflammation in patients with alzheimer's disease: A randomized, single-blinded, placebo-controlled trial
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Notably, anti-ageing mechanisms by which metformin can activate the gerosuppressor/tumor suppressor AMPK

43 , e47e47 (2015)
2.5 Optic nerve injury Irreversible visual impairment and blindness occur as a result of optic nerve injury, with RGC death being a crucial pathological initiator