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For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges

Ann Bot 116(3):369376 Mittler R (2017) ROS are good

Reliability of malondialdehyde as a biomarker of oxidative stress in psychological disorders

This can lead to improved respiratory function and a potentially reduced need for pharmaceutical medications

Paszczyca, A

Structureactivity relationship studies indicate that potential nitrile oxide species derived from diacylfuroxan bind specifically to the catalytic (seleno)cysteine residue 46 of GPX4 [219]