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It has been safely used in a number of preclinical and clinical trials

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The objective of this review is to critically assess the current evidence surrounding their mechanisms of action, clinical indications, efficacy, and safety profiles, with particular emphasis on regulatory and translational considerations

It is stable to autoclaving for short periods at 121C

Reprint of: biogenesis of the cytochrome bc1 complex and role of assembly factors

Intra-articular delivery of AAV vectors encoding PD-L1 attenuates joint inflammation and tissue damage in a mouse model of rheumatoid arthritis