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Experimental data have demonstrated that co-occurrence of EGFR amplification and PTEN loss may be synergistic and predispose to chromosomal instability and an aggressive GBM phenotype (43)

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However, this effect is temporary and superficial

But knowing which file-sharing methods to use can be challenging when youre facing a bowl of alphabet soup: FTP vs FTPS vs SFTP

this does not obviate the need for specific therapy in such conditions

Based on these findings, a reintroduction of chloroquine as a part of combination therapies may be an effective treatment strategy