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It was created initially as an anti-obesity medication

Dan Wool, NMD Arizona-licensed Naturopathic Physician and Gastroenterology Specialist Updated: February 26, 2026 Summary (tl;dr): What AOD-9604 Is and How It Works: AOD-9604 is a synthetic 16-amino acid fragment of human growth hormone (hGH) specifically amino acids 176191 engineered to target fat metabolism

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Lastly, NNMT overexpression unregulated CDK2 and CDK6 expression and downregulated P15, P21, and P27 expression, contributing to the imbalance between CDK and CKI
