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Furthermore, Ewell [118] demonstrated that endogenous ADAP1 localizes with markers of regulated secretory granules such as chromogranin B, furin, and AP-3 in primary culture hippocampal neurons

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This FDA review signals a shift

Understanding the interplay between iron metabolism, FPN regulation, and ferroptosis will be essential in devising effective interventions for OA and other iron-related pathologies

In summary, the interaction of polyphenols with mitochondrial components helps boost ATP production and also plays a protective role by mitigating oxidative stress (Fig
