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The use of ROS inhibitors effectively counteracted the enhancement of A-induced IL-1 release by iron and prevented the activation of NF-B and mitogen-activated protein kinase (MAPK) in microglia [93, 94], highlighting the critical role of oxidative stress in microglial inflammation

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USA 113 , 1152511530 (2016)

107 In the presence of oxygen, HIF-1 is hydroxylated, followed by a ubiquitination reaction, leading to the proteolysis of HIF1 through the ubiquitinproteasome system

(2001) 51:505P

Providing young adults with knowledge about the dangers of recreational ketamine use helps reduce misuse