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In regard to AT-III, studies indicate that AT-III can promote the expression of pro-apoptotic genes such as Bax, caspase-2, and caspase-9 while inhibiting the expression of anti-apoptotic gene Bcl-2

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The incubation of astrocytes with gp120 enhanced the mRNA and protein levels of ABCC1

It's funny, I was trying to figure this stuff out but it was a bit like fumbling in the dark - I had never tried predicting binding properties but my search led me to SwissDock

[Abstract]2022 Jul 22;11(4):673-682

doi: 10.7164/antibiotics.47.301
