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Several potential therapeutic targets related to cholesterol ester metabolism have been identified, including: Acyl-CoA:Cholesterol Acyltransferase (ACAT) : Inhibitors of ACAT, such as avasimibe and pactimibe, reduce cholesterol ester synthesis and intracellular lipid accumulation, offering potential benefits for reducing atherosclerosis progression and improving lipid profiles

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doi:10.1038/sj.ijir.3900582

FIGURE 5 It can be seen from Figure 5B that the sensitivity of immobilized CRL to temperature is reduced

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