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doi:10.3109/07420528.2014.957304

introduced Zr into a manganese porphyrin-based MOF (Mn-MOF) to construct a biocompatible nanosensitizer along with the capacity of GSH exhaustion-enhanced ferroptosis (Figure 5F) (Figure 5G), thus elevating Mn-MOF-induced ROS concentration, leading to the deactivation of GPX4 and ROS-enhanced ferroptosis

These ADME characteristics imply that bioactive forms present in systemic circulation often differ significantly from the ingested compound, consisting instead of complex mixtures of conjugated and microbial-derived metabolites

[DOI] [PubMed] [Google Scholar] Rumpf, J

Blood 110 , 401408 (2007)

CRISPR/Cas9-mediated homology-directed genome editing in Pichia pastoris
