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Graphical Abstract Keywords Transaminases, Vitamin B 6 , Celiac disease, Renal insufficiency, Hepatolenticular Degeneration, Crohn disease, Malnutrition, Clofibrate, Bone diseases, Lead poisoning, Anemia, Hemolytic Introduction Liver disease is often detected using automated assays of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl transpeptidase (GGT) and 5-nucleotidase (5-NT)

The combined treatment with taurine and niacin blocks the bleomycin-induced activation of nuclear factor-kappaB and lung fibrosis

SOX6, SRY-box transcription factor 6

demonstrated that the injection of adeno-associated virus (AAV) vectors carrying the genes for NURR1 and FOXA2 into the substantia nigra (SN) of a PD mouse model revealed that these two factors collaborate to enhance dopaminergic neuron survival

In the context of tumor immune microenvironment remodeling, the SSP induces an immunosuppressive phenotype, promotes M2-type macrophage polarization, sustains high PD-L1 expression, impairs the cytotoxic function of CD8 + T cells, and compromises the therapeutic efficacy of CAR-T cells