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Vitamin C is required for the production of collagen, a structural protein found in the epidermis, bones, tendons, and blood vessels

Moreover, the TGF-beta signaling pathway regulates a broad spectrum of cellular functions such as proliferation, apoptosis, differentiation and migration (63)

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ROS are the main molecules involved in the role and mechanism of GPxs in the development of diseases ROS, reactive oxygen-containing molecules, are the normal products of aerobic reactions in humans, such as oxidative respiration in mitochondria [24]

One potential undesired process is insulin fibril formation

Twelve mice were randomly divided into 4 groups and injected into the tail vein with PBS, Ru(II)-OH, NP2, and NP4 (2 mg Ru/kg) on the days 1, 4, and 7