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Parkinsons disease (PD) had disrupted purine and tryptophan metabolism, oligomeric alpha-synuclein and neurofilament light chain expression compared to neurodegenerative diseases 63

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Furthermore, the resulting chlorinative stress may lead to multiorgan damage in COVID-19 through various mechanisms, including oxygen competition for heme-binding sites, decreased oxygen saturation, hemoglobin-heme iron oxidation, heme degradation, and iron release [88]