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10.1016/j.cmet.2013.12.002 Cell Metab

The poor clinical outcomes are largely attributed to the tumors intrinsic resistance to therapy, driven by factors such as blood-brain barrier (BBB) impermeability, cellular heterogeneity, and the persistence of glioma stem cells (GSCs)

Furthermore, the findings suggested that DAPA may attenuate HG-induced ferroptosis and mitigate histological damage and functional abnormalities in the kidneys of diabetic nephropathic mice, both in vivo and in vitro

, UlloqueBadaracco, J

E., McLane L
SARS-CoV-2 infection reprograms host folate and one-carbon metabolism at the PTM level to support de novo purine synthesis for replication of viral genome, through bypassing the viral shutoff of host translation 37
